NOTCH-RBP-J SIGNALING REGULATES THE MOBILIZATION AND FUNCTION OF ENDOTHELIAL PROGENITOR CELLS BY DYNAMIC MODULATION OF CXCR4 EXPRESSION IN MICE.

Notch-RBP-J signaling regulates the mobilization and function of endothelial progenitor cells by dynamic modulation of CXCR4 expression in mice.

Bone marrow (BM)-derived 730 sunken lake road endothelial progenitor cells (EPC) have therapeutic potentials in promoting tissue regeneration, but how these cells are modulated in vivo has been elusive.Here, we report that RBP-J, the critical transcription factor mediating Notch signaling, modulates EPC through CXCR4.In a mouse partial hepatectomy

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The Power of Professors and Professionals: How Professions Shape Organizational Systems in Elite University Admissions

Elite university admissions are administered by a range of organizational actors depending on chervo jacke herren national and institutional contexts.While the outcomes of high-stakes elite university admissions have been studied extensively, the opaque admissions selection process remains undertheorized and understood.Using theories of professions

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Retrospective application of transposon-directed insertion-site sequencing to investigate niche-specific virulence of Salmonella Typhimurium in cattle

Abstract Background Salmonella enterica subspecies enterica read more is an animal and zoonotic pathogen of global importance.Cattle are a significant reservoir of human non-typhoidal salmonellosis and can suffer enteric and systemic disease owing to the ability of Salmonella to survive within the bovine lymphatic system and intestines.Contaminatio

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